Research finds aspirin successfully prevents clots after joint surgery

November 8, 2012

Topic: total joint replacement surgery

Research finds aspirin successfully prevents clots after joint surgery

Patients who undergo total joint replacement surgery are normally prescribed a blood thinner to take before the procedure to decrease their risk of clots. In the past, doctors have stuck with traditional drugs like warfarin, but now they may have a safer, less expensive option - aspirin.

Researchers from the Rothman Institute at Jefferson looked at the outcomes of more than 26,000 patients who had a joint replacement procedure between 2000 and 2011, some of whom received aspirin while others were given warfarin. They discovered that aspirin is just as successful in preventing clots as the conventional medication.

In addition, aspirin does not have as many side effects as warfarin, which may cause increased bleeding, infections and hospital readmissions, as well as necrosis or gangrene, according to the National Institutes of Health.

"Our study shows that aspirin is a viable alternative to warfarin in healthy patients, with better results in preventing clots, and a lower rate of bleeding and wound complications," said lead study author Javad Parvizi, M.D. "It will allow all us to move away from expensive, inconvenient and dangerous drugs in the prevention of thromboembolism after joint replacement."

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